2 Methoxycinnamic Acid

2-Methoxycinnamic acid has a wide range of main uses. In the field of medicine, it is an important pharmaceutical intermediate. It can participate in the synthesis of many drugs with special curative effects through specific chemical reactions, such as some drugs used to regulate human physiology and fight specific diseases. It occupies a key position in the chemical synthesis of drugs, like the cornerstone of a high-rise building. Without it, it is difficult to build a complete and effective drug molecular structure.
In the cosmetic industry, 2-methoxycinnamic acid also plays an important role. Because of its good ultraviolet absorption properties, it is often used in the preparation of sunscreen cosmetics. It can effectively absorb ultraviolet rays in the band of greater damage to the skin, such as medium wave ultraviolet rays (UVB), like an invisible umbrella company for the skin, reduce ultraviolet damage to the skin, prevent skin problems such as sunburn, tanning, photoaging, etc., so as to protect the health and beauty of the skin.
Furthermore, in the field of organic synthesis, 2-methoxy cinnamic acid, due to its unique molecular structure and rich in reactive functional groups, can be used as a key raw material to prepare a variety of functional organic compounds through various organic reactions, such as esterification and addition reactions. These compounds have important uses in materials science, fine chemistry, and many other fields, greatly expanding the boundaries of organic synthesis and providing a rich material basis for the development of many fields.

2-Methoxy cinnamic acid is one of the organic compounds. Its physical properties are particularly important and are described as follows:
Looking at its properties, under room temperature and pressure, 2-methoxy cinnamic acid is white to light yellow crystalline powder, fine and uniform, which is easy to identify and operate.
When talking about the melting point, it is between 170-174 ° C. The characteristics of the melting point are like the "marking temperature" of the substance. When the temperature rises, the substance gradually melts from the solid state to the liquid state. This change is clearly observable and is an important basis for the identification and purification of the substance.
As for solubility, it is slightly soluble in water, which is due to the weak interaction between the polarity of water molecules and the molecular structure of 2-methoxy cinnamic acid. However, it is soluble in organic solvents such as ethanol, ether, and ethyl acetate. The molecular structure of organic solvents such as ethanol, ether, and ethyl acetate is similar to that of 2-methoxy cinnamic acid. According to the principle of "similar miscibility", the substance can be well dispersed in such solvents. This solubility lays the foundation for its application in organic synthesis, drug preparation, and other fields.
Looking at its density, although there is no exact value of the common saying, it is inferred according to its molecular composition and the properties of similar compounds. The density is different from that of water, and there may be subtle changes under different conditions. Although this is not a key characterization, it cannot be ignored in accurate experiments and applications.
In addition, 2-methoxy cinnamic acid is relatively stable in air, and may undergo chemical changes under extreme conditions such as hot topics and open flames. It is also sensitive to light. Long-term light or structural changes affect its chemical properties and application effects. Therefore, when stored, it should be placed in a cool and dark place.

2-Methoxy cinnamic acid, this is an organic compound with interesting chemical properties.
It is acidic because it contains a carboxyl group (-COOH), which can release protons and exhibit acidic properties in aqueous solutions. It can react with bases to form corresponding salts and water. For example, by reacting with sodium hydroxide, sodium 2-methoxy cinnamic acid and water can be obtained.
2-methoxy cinnamic acid stores a carbon-carbon double bond, which gives it a lively chemical activity. Addition reactions can be carried out. If it encounters bromine water, the carbon-carbon double bond is opened, and bromine atoms are added to it, causing bromine water to fade. It can also participate in the polymerization reaction, and many monomers containing carbon-carbon double bonds can be added and polymerized with each other to form polymer compounds. The presence of methoxy (-OCH)
also affects its properties. Methoxy is a power supply group, and through the induction effect and conjugation effect, it has an effect on the electron cloud density distribution of the benzene ring, which increases the electron cloud density of the adjacent and para-position of the benzene ring, and then makes the benzene ring more prone to electrophilic substitution reactions, such as halogenation, nitrification, sulfonation, etc., and the reaction check point tends to be the neighbor and para-position of the methoxy group.
In addition, 2-methoxycinnamic acid has a characteristic absorption in the ultraviolet region due to its conjugated system, which makes it useful as an ultraviolet absorber in the field of analytical chemistry. Its solid state is a crystalline solid with a certain melting point, and the exact value of the melting point can be used as an important physical constant for identifying the compound. In organic solvents, according to the principle of similarity compatibility, it can be soluble in some polar organic solvents, such as ethanol and acetone, but the solubility in water is relatively small.

The preparation method of 2-methoxycinnamic acid is the key to the chemical process. To make this acid, organic synthesis is often followed. One method is to use p-methoxybenzaldehyde and malonic acid as raw materials, and carry out Knoevenagel condensation reaction under the catalysis of organic bases such as pyridine and hexahydropyridine. This reaction mechanism is exquisite. The carbonyl group of p-methoxybenzaldehyde is affected by the base, and interacts with the active methylene of malonic acid. After condensation and loss of water, 2-methoxycinnamic acid is obtained.
The process is as follows: First, put p-methoxybenzaldehyde and malonic acid in a reaction vessel in an appropriate ratio, and add an appropriate amount of pyridine or hexahydropyridine as a catalyst. The reaction temperature is usually controlled in a moderate range, generally between 80 and 120 degrees Celsius. In this temperature range, the reaction rate and product yield can be appropriate. During the reaction, the reaction process can be closely monitored, which can be observed by means of thin-layer chromatography. After the reaction is completed, the product can be purified by conventional post-treatment methods, such as acidification, extraction, recrystallization, etc., to obtain pure 2-methoxy cinnamic acid.
Or there are other methods, using p-methoxy styrene as the starting material, prepared by oxidation reaction. Suitable oxidizing agents, such as potassium permanganate, potassium dichromate, etc. Under specific reaction conditions, the double bond of p-methoxy styrene is oxidized, and the carboxyl group is introduced to obtain 2-methoxy cinnamic acid. However, this approach requires fine regulation of the reaction conditions. Due to the strong oxidation of the oxidant, it is easy to cause side reactions such as excessive oxidation, which affects the purity and yield of the product. Therefore, when operating, the amount of oxidant, reaction temperature and reaction time should be carefully controlled to achieve the best preparation effect.

It is difficult to determine the price range of 2-methoxycinnamic acid in the market. The price of 2-methoxycinnamic acid often changes due to various reasons, such as the quality of the goods, the situation of supply and demand, the amount of purchase, and even the market conditions.
If its quality is high, it meets various strict standards, and there are many people in the market, but the supply is small, the price will be high. On the contrary, if the quality is ordinary, the supply is abundant, and the demand is not strong, the price will decrease.
The purchase volume is also a major factor. If buyers ask for it in large quantities, the merchant may give a discount in order to promote sales, and the price may drop. However, if you ask for it in small quantities, the price may remain at the same level.
Looking at past market conditions, its price fluctuated between tens of yuan and hundreds of yuan per kilogram. However, this is only an approximate number, and it is difficult to accurately determine.
To determine its market price, you can consult a merchant specializing in chemical raw materials, or observe the price announced by the chemical product trading platform, so that you can get a near-real price.