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4-Chlorocinnamic Acid

Juelun Chemical

Specifications

HS Code	812590
Chemical Formula	C9H7ClO2
Molar Mass	182.603 g/mol
Appearance	Yellow to off - white crystalline powder
Solubility In Water	Slightly soluble
Solubility In Organic Solvents	Soluble in ethanol, ether, etc.
Melting Point	247 - 251 °C
Boiling Point	Decomposes before boiling
Pka	4.33
Density	1.348 g/cm³
Odor	Odorless

Packing & Storage

Packing	500g of 4 - Chlorocinnamic Acid packaged in a sealed, chemical - resistant container.
Storage	4 - Chlorocinnamic acid should be stored in a cool, dry, well - ventilated area. Keep it away from sources of heat, ignition, and direct sunlight. Store in a tightly closed container to prevent moisture absorption and contamination. It should be separated from oxidizing agents and incompatible substances to avoid chemical reactions.
Shipping	4 - Chlorocinnamic Acid is shipped in sealed, corrosion - resistant containers. Care is taken to prevent physical damage. Shipments adhere to chemical transportation regulations to ensure safe transit.

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General Information

Historical Development

4-Chloro-cinnamic acid is also a chemical product. Its origin can be traced back to the past. At the beginning, the academic community became more and more deeply involved in organic synthesis, and many chemists devoted themselves to exploring new compounds. At that time, the field of organic chemistry was booming, and various synthesis methods were introduced.
Everyone paid attention to cinnamic acid derivatives when aromatic compounds were synthesized. After repeated experiments and investigations, chlorine was introduced into the structure of cinnamic acid, resulting in 4-chloro-cinnamic acid.
With the passage of time, research has become more and more refined. Its physicochemical properties were analyzed in detail, and its characteristics under different reaction conditions were also clearly observed. This product has emerged in many fields such as medicine and materials, and its application path has gradually expanded. Since its original novelty, it has been indispensable in industrial production and scientific research, witnessing the vigorous development of the chemical field.

Product Overview

4-Chlorocinnamic acid is also a chemical product. Its shape and color are white to off-white crystalline powder, which is pure, delicate and uniform. Stable in nature, when exposed to heat, open flame or oxidant, be careful to prevent accidents.
This product is widely used in the field of organic synthesis. It is often used as a raw material for the preparation of medicines, pesticides, fragrances and other substances. In medicine, or it can be involved in the research of disease treatment; in pesticides, or it is related to the needs of crop protection; in fragrances, or it can add fragrance.
The method of preparation is based on the path of chemistry and is formed through various reactions. The process requires precise control of conditions, such as temperature, pH, etc., in order to obtain high-quality products. The obtained product, if it meets the specifications, can be a treasure of the chemical industry and help the prosperity of all industries.

Physical & Chemical Properties

4-Chloro cinnamic acid is also an organic compound. It is usually a white to light yellow crystalline powder with certain physical and chemical properties.
In terms of melting point, it is about 245-248 ° C. This property makes it undergo a phase transition at a specific temperature. In terms of solubility, it is slightly soluble in water, but it can be soluble in organic solvents such as ethanol and ether. This is because it is similar to each other. In terms of chemical properties, 4-chloro cinnamic acid contains carbon-carbon double bonds and carboxyl groups, which can participate in many chemical reactions. Carbon-carbon double bonds can undergo addition reactions, such as addition with hydrogen to form saturated compounds; carboxyl groups can undergo esterification reactions, and alcohols can form esters under the action of catalysts. Due to its unique physical and chemical properties, it has applications in the fields of medicine, fragrance, etc. It can be used as a pharmaceutical intermediate to synthesize specific drugs, and can also provide raw materials for fragrance synthesis, which is of high research value.

Technical Specifications & Labeling

4-Chlorocinnamic acid is an important organic compound. Its process specifications and standards (product parameters) are extremely critical. The preparation of 4-chlorocinnamic acid requires a specific process. The selection of raw materials should accurately consider its purity and characteristics. The reaction conditions, such as temperature, pressure, catalyst dosage, etc., must be strictly controlled. The reaction temperature should be maintained in a specific range, the pressure should also be stable in a suitable range, and the amount of catalyst needs to be precisely prepared to ensure the efficient progress of the reaction.
In terms of product standards, the appearance should be a specific color state, the purity must reach a corresponding high standard, and the impurity content must be strictly limited. In this way, high-quality 4-chloro cinnamic acid products can be produced to meet the application needs of different fields and play an important role in the chemical, pharmaceutical and other industries.

Preparation Method

The preparation method of 4-chloro-cinnamic acid is related to the raw materials and production process, reaction steps and catalytic mechanism. The raw materials are selected, when cinnamic acid and an appropriate amount of chlorinated reagents are used, the two are the basis for the reaction.
In the production process, cinnamic acid is first placed in a reactor and dissolved in an organic solvent to make a homogeneous system, so that the reaction is sufficient. Then, slowly add chlorinated reagents, and control the temperature at the same time, usually under moderate warm conditions, about 50-80 degrees Celsius, to prevent side reactions from occurring.
The reaction steps are as follows. The chlorinated reagent and cinnamic acid are electrophilically replaced, and the chlorine atoms are cleverly inserted into the cinnamic acid benzene ring to obtain 4-chloro-cinnamic acid crude After separation and purification, such as recrystallization, to achieve high purity products.
In the catalytic mechanism, specific catalysts, such as Lewis acids, can be introduced to activate chlorination reagents, reduce the reaction energy barrier, promote the efficient reaction, and improve the yield and purity of 4-chlorocinnamic acid. In this way, 4-chlorocinnamic acid can be prepared through these operations.

Chemical Reactions & Modifications

4-Chlorocinnamic acid is also an organic compound. Its chemical reaction and modification are the most important research of our generation.
To observe its chemical reaction, under suitable conditions, 4-chlorocinnamic acid can be involved in addition and substitution. If it encounters nucleophiles, the benzene ring or a specific part of the side chain can be substituted, which can lead to changes in its structure and then change its properties.
On its modification, or by introducing different groups into the molecular structure, to change its physical and chemical properties. After modification, it can increase its solubility, stability, or change its biological activity. This is of great significance in the fields of medicine, pesticides, etc. After careful study and modification, it is expected to expand its use, increase its value, and contribute to the progress of chemistry and related fields.

Synonyms & Product Names

4-Chlorocinnamic acid is also the product of transformation. Its synonym and trade name are related to the identification of this thing, and also involve the cognition of the industry.
In the process of research, it often encounters the situation of synonym of the same thing. 4-Chlorocinnamic acid, or has another name for various situations. For example, due to the different production methods and uses, or get different names.
Guanfu City, the name of the business also shows its own state. Or according to the quality and characteristics, it is named with a special name, hoping to attract people's attention and distinguish it from others.
The synonym of the same thing is not only a common phenomenon in the industry, but also a matter that researchers should know. The same name and commercial name of 4-chlorocinnamic acid are used in research and in the heart, so as not to be confused. It is necessary to walk freely in the chemical industry and explore its various wonders to promote the prosperity of this industry.

Safety & Operational Standards

4-Chlorocinnamic acid is also one of the chemical drugs. Its safe production and operation standards are of great importance.
At the beginning of preparation, all raw materials must be checked in detail. Purity and characteristics must meet the standards, and there should be no slight difference. When taking it, according to the exact amount, do not make excessive or insufficient, causing the reaction to be biased.
The reaction device must be clean and unstained, and the previous residue must be washed away. The temperature of heating should be carefully controlled. Gradually rise and fall, follow the rules, and must not be changed abruptly. If the temperature is too high, the product may decompose; if it is too low, the reaction will be slow and affect the yield.
When stirring, the rate should be uniform. If it is too fast, the material will splash, and there is a risk of injury; if it is too slow, the reaction will be uneven and the quality will be difficult to control.
Furthermore, the reaction environment should not be ignored. The ventilation must be good, and the harmful gases should be dissipated immediately to avoid poisoning.
The product is ready, separated and purified, and also follows the specifications. The reagents used should be harmless. When operating, be careful to prevent its loss.
When storing, choose an appropriate location. Avoid light, shade, and keep away from fire sources. The packaging is sealed to prevent deliquescence and oxidation.
The safe production and operation of 4-chlorocinnamic acid are interlinked and cannot be sloppy at all. In this way, the safety of production and the quality of products can be guaranteed.

Application Area

4-Chlorocinnamic acid is used in various fields such as medicine, fragrance, and chemical industry.
In medicine, it is a key raw material for the synthesis of many special drugs. Due to its unique chemical structure, it can accurately participate in the construction of drug molecules and enhance drug efficacy. For example, it can help develop antibacterial and anti-inflammatory drugs, effectively fight various bacteria, reduce human inflammation, and protect health.
In the field of fragrances, 4-chlorocinnamic acid has been delicately blended to endow fragrances with a unique and charming aroma. Either for fresh floral fragrance, or for rich fruity fragrance, it adds fragrance to perfumes, air fresheners and other products, pleasing the sense of smell.
In chemical industry, it is an important component in the synthesis of high-performance materials. With its reactivity, it can prepare materials with strong stability and excellent performance, which are widely used in coatings, plastics and other industries to improve product quality and durability.
From this point of view, 4-chloro cinnamic acid plays an important role in various application fields.

Research & Development

In recent years, I have focused on the research of 4-Chlorocinnamic Acid. This material is unique, has a wide range of uses, and can be used in various fields of medicine and chemical industry.
Initially, analyze its structure and explore its characteristics, but the preparation method is difficult and inefficient. I then decided to improve it. After months of study, I tried various paths and adjusted various parameters.
Fortunately, the new method is simple and efficient, and the yield is also increased. However, I did not dare to be complacent, and considered the possibility of mass production, thinking about the adaptation of equipment and the optimization of process.
I believe that with time and continuous improvement, 4-Chlorocinnamic Acid will be able to emerge in more fields, contributing to the development of the industry and pushing it to a new level.

Toxicity Research

4-Chloro-cinnamic acid, its toxicity research is related to people's livelihood. I have studied it in this country to observe its properties in detail.
At the beginning, I tested it with various experiments. Apply this substance to various kinds of creatures and observe its changes. Take white mice as an experiment and feed them a diet containing 4-chloro-cinnamic acid. For a few days, the appearance of white mice was observed, and their diet and actions were slightly different. The amount of food they ate was slightly reduced, and their walking was also slow.
Analyze its shadow in the environment. Place it in water and soil to observe the transformation of water and soil. The quality of water gradually changes, and the life of microorganisms in the soil is also disturbed by it.
Furthermore, explore the harm of its entry into the body. Simulate the environment of the human body and study its response to cells. It is seen that it is harmful to the growth and metabolism of some cells, or causes cell abnormalities.
In summary, the toxicity of 4-chlorocinnamic acid should not be underestimated, and it has an impact on living beings and the environment. Follow-up research should be done to find ways to avoid harm and ensure the safety of all living beings and the environment.

Future Prospects

4-Chlorocinnamic acid, the future development of this material, my heart is looking forward to it. Looking at its chemical properties, it has a unique reaction ability, or it can be created in new materials to show its brilliance. In the field of materials, with the advancement of science and technology, seeking new and unique properties, 4-chlorocinnamic acid has a unique structure, or is the basis for the development of tough and lightweight materials with specific properties. It can be used in aerospace and electronic equipment.
In addition, the road of medical exploration also has potential. Today, the fight against diseases continues to deepen, and drug innovation is imminent. The chemical properties of 4-chlorocinnamic acid may lead to the birth of new drugs to fight difficult diseases and seek well-being for human health. In the future, through in-depth research, we will be able to explore its capabilities in the field of materials and medicine, shining brightly and being used by the world.

Frequently Asked Questions

What are the main uses of 4-Chlorocinnamic Acid?

4-Chlorocinnamic acid, which has a wide range of uses. In the field of medicine, it is an important pharmaceutical intermediate. The special chemical structure of 4-chlorocinnamic acid can be converted into compounds with specific pharmacological activities through many chemical reactions. For example, it can be used to synthesize some antibacterial drugs. Through its structural modification, the inhibitory effect of the drug on specific bacteria can be enhanced to deal with various infectious diseases.
In the chemical industry, 4-chlorocinnamic acid is also indispensable. It is often used as a key raw material in organic synthesis to prepare a variety of fine chemicals. Such as the synthesis of polymer materials with special properties, by introducing 4-chloro cinnamic acid into the polymer structure, the material is endowed with unique physical and chemical properties, such as improving the heat resistance and corrosion resistance of the material.
Furthermore, in the field of fragrances, 4-chloro cinnamic acid can play its unique role. Because of its own or the products derived from chemical reactions, it has a special aroma and can be used to prepare various flavors and fragrances, adding a unique fragrance to perfumes, cosmetics, etc., and enhancing the quality and attractiveness of products.
In addition, in agriculture, 4-chloro-cinnamic acid can be properly converted or can be prepared into biologically active substances for use in the synthesis of plant growth regulators or pesticides to help crops grow, resist pest attacks, and ensure agricultural harvests.

What are the Physical Properties of 4-Chlorocinnamic Acid?

4-Chlorocinnamic acid is a kind of organic compound. It has unique physical properties and has important uses in many fields.
In terms of its properties, 4-chlorocinnamic acid is white to light yellow crystalline powder, which is easy to observe and identify. It is relatively stable under normal conditions, but will change under special conditions.
Its melting point is about 248-250 ° C. The melting point is an inherent property of the substance. This specific melting point value can be used as a key basis for identifying 4-chlorocinnamic acid. In chemical experiments and industrial production, the purity of the substance can be determined by measuring the melting point.
In terms of solubility, 4-chlorocinnamic acid is slightly soluble in water, but soluble in organic solvents such as ethanol and ether. This solubility property is closely related to the molecular structure. Due to the presence of specific groups in the molecule, it interacts differently with water and organic solvents. In practical applications, such as extraction, separation and reaction processes, the solubility characteristics affect its operation method and process.
The smell of 4-chlorocinnamic acid also has characteristics, with a weak aromatic smell. Although the smell is not its key property, it has a certain impact on the sensory aspects of the product, and may be considered in the field of fragrance preparation.
In summary, the physical properties of 4-chlorocinnamic acid, such as morphology, melting point, solubility, and odor, are of great significance for its identification, application, and related research, which can help chemists better understand and use this compound.

What are the Chemical Properties of 4-Chlorocinnamic Acid?

4-Chlorocinnamic acid is also an organic compound. Its properties have a specific appearance and characteristics.
Under normal temperature, 4-chlorocinnamic acid is mostly white to light yellow crystalline powder, fine and uniform. Its stability in air is still good, but it also poses risks in case of hot topics and open flames, so it needs to be handled with caution.
When it comes to solubility, 4-chlorocinnamic acid is slightly soluble in water, but it has good solubility in organic solvents such as ethanol, ether, and chloroform. This property is of great significance in the extraction and separation steps of organic synthesis, and can help chemists to operate according to its characteristics.
As for chemical activity, the molecule of 4-chloro-cinnamic acid contains carbon-carbon double bonds and carboxyl groups, both of which are active groups. Carbon-carbon double bonds can participate in addition reactions, such as addition with hydrogen halides, halogens, etc., to form new halogenated hydrocarbons. The carboxyl group is also active and can be neutralized with bases to produce corresponding carboxylic salts; it is esterified with alcohols to obtain ester compounds. And because of the presence of chlorine atoms, it can add reactivity and introduce new functional groups, opening a broad path for organic synthesis.
The chemical properties of 4-chloro-cinnamic acid make it useful in medicine, flavors, pesticides and other fields. In medicine, it can be used as an intermediate to produce drugs with special curative effects; in fragrances, it can be modified into ingredients with unique aromas based on its structure; in the field of pesticides, it may be a key raw material for the synthesis of high-efficiency and low-toxicity pesticides.

What is the Production Method of 4-Chlorocinnamic Acid?

The preparation method of 4-chloro-cinnamic acid has its own methods in various techniques in the past. One common method is to use 4-chlorobenzaldehyde and malonic acid as raw materials, and carry out Knoevenagel condensation reaction under the catalysis of organic bases such as pyridine or hexahydropyridine. In this reaction, the aldehyde group of 4-chlorobenzaldehyde interacts with the active methylene of malonic acid, and after condensation and dehydration, 4-chloro-cinnamic acid is obtained. During the reaction, it is necessary to pay attention to the control of temperature. Generally, under moderate heating conditions, the reaction can be smoothly advanced. However, if the temperature is too high, it may cause side reactions and lead to impure products.
The second method is to use 4-chlorophenylvinyl as the starting material and oxidize it. The carbon-carbon double bond of 4-chlorostyrene is oxidized in a suitable reaction medium, such as potassium permanganate or potassium dichromate, and then carboxylated to form 4-chloro cinnamic acid. However, this approach requires fine regulation of the amount of oxidant and reaction conditions. Due to the strong oxidizing properties of the oxidant, if improperly disposed, it is easy to over-oxidize, which damages the yield and purity of the product.
Furthermore, 4-chloroacetophenone is also used as a raw material. First, 4-chloroacetophenone is converted into the corresponding enol structure, and then 4-chloro cinnamic acid can be obtained through specific oxidation and subsequent treatment steps. This process involves a multi-step reaction, and the reaction conditions at each step, such as pH, temperature, reaction time, etc., all have a significant impact on the quality and yield of the final product.
All these preparation methods have their own advantages and disadvantages. In actual production, according to the availability of raw materials, cost considerations, product purity requirements and many other factors, the appropriate preparation process is carefully selected to achieve the purpose of efficient and high-quality production of 4-chlorocinnamic acid.

What is the price range of 4-Chlorocinnamic Acid in the market?

4-Chloro cinnamic acid is in the market, what is the price? The price in the market often varies with time, place and quality. In the past, 4-chloro cinnamic acid in the market of chemical materials, if the quality is high and the quantity is abundant, the price may be between tens and hundreds of yuan per kilogram. If it is retail in small quantities and resold layer by layer, the price may rise, and the price per gram can reach several yuan.
However, the chemical market is unpredictable and changing like the wind and cloud. The price of raw materials, the novelty of the process, and the trend of demand can all make the price fluctuate. If the raw materials are easily available, the process is refined, and the quantity of production increases, the price may decrease. On the contrary, if the raw materials are scarce, it is difficult to increase the system, and there are many applicants and few suppliers, the price will increase.
And in different places, the price is also different. In prosperous business cities, logistics is convenient, transactions are frequent, or the price is flat due to competition. In remote places, transportation is difficult, costs are superimposed, and the price may be high. To know the exact price, when you consult chemical material firms, trading houses, or the network of chemical transactions, you can get a real-time price, so as not to be mistaken by false prices.