4 Methylcinnamic Acid

4-Methylcinnamic Acid is 4-methylcinnamic acid, and its chemical structure is as follows.
4-methylcinnamic acid, a derivative of cinnamic acid. The structure of cinnamic acid is that the benzene ring is connected to a carboxyl group through a carbon-carbon double bond, and 4-methylcinnamic acid is introduced at the No. 4 position of the cinnamic acid benzene ring (that is, the para-position of the benzene ring carbon connected to the carbon-carbon double bond).
In ancient terms, in the structure of this compound, there is a benzene ring, the ring has six carbons, and is linked by a covalent bond, forming a ring shape. The carbon on the ring is connected to the terminal carbon of the one-carbon-carbon double bond, and the other carbon of the double bond is then related to the carboxyl-COOH, which is the basic structure of cinnamic acid. In the counterposition of the carbon connected to the benzene ring and the double bond, there is a methyl-CH 🥰 attached, which is the unique structural feature of 4-methyl cinnamic acid. The addition of methyl to the benzene ring makes its physical and chemical properties easier than that of cinnamic acid. In the fields of organic synthesis, medicinal chemistry, etc., due to this structural characteristic, it shows specific properties and uses.

4-Methylcinnamic acid, which has a wide range of uses. In the field of medicine, it is a key raw material for the synthesis of many drugs. For example, some drugs with anti-inflammatory and antioxidant effects are often involved in the synthesis path of 4-methylcinnamic acid. Due to its special chemical structure, it can be converted into pharmaceutical active ingredients through a series of reactions, helping the human body resist inflammation and maintain the balance of oxidation and antioxidation in the body.
In the field of materials, it also plays an important role. It can be used to prepare polymer materials with excellent performance. By polymerizing with other monomers, polymer materials can give unique optical and thermal properties. For example, the prepared material may have good photostability, and it is not easy to decompose and change color under light environment, laying the foundation for the application of the material in outdoor facilities, optical instruments, etc.
Furthermore, in the fragrance industry, 4-methyl cinnamic acid is also useful. Because of its own special aroma, it can become an integral part of the fragrance formula after formulation and processing. Its unique and long-lasting aroma can add a different flavor to the fragrance, and is widely used in perfumes, air fresheners and other products to enhance the olfactory experience of products.
In addition, in the agricultural field, it can be used as a raw material for plant growth regulators. After rational development, the prepared regulators may affect the process of plant growth and development, such as promoting plant root growth, enhancing plant stress resistance, helping to increase crop production and income, and providing effective assistance for agricultural production.

4-Methylcinnamic acid is also an organic compound. It has unique physical properties, so let me tell you in detail.
Looking at its appearance, 4-methylcinnamic acid is often white to light yellow crystalline powder, which is quite recognizable in many organic compounds. It is like a pearl hidden in dust and sand, and it is unique.
As for the melting point, it is about 198-200 ° C. When the temperature gradually rises, this substance melts like ice in the spring sun, gradually turning from solid to liquid. This melting point characteristic is a key indicator in the process of identification and purification, like a navigational compass, guiding chemists to explore its mysteries.
Solubility is also an important physical property. 4-Methyl cinnamic acid is slightly soluble in water, but it can be better dissolved in organic solvents such as ethanol and ether. This difference in solubility is quite similar to a person's choice of friends. It is slightly alienated in the water environment and can get along well in the atmosphere of organic solvents. Because it is slightly soluble in water, it is often suspended as solid particles in the aqueous phase system; while in the organic solvent, the molecules can be dispersed and shuttle freely. This property is of great significance in organic synthesis and separation operations.
Its density is moderate, although there is no exact extraordinary thing, it is also a piece of the overall puzzle of its physical properties, and it is indispensable when considering its behavior of ups and downs and mixing in different media.
In addition, 4-methyl cinnamic acid is relatively stable under normal temperature and pressure. However, under specific conditions, such as high temperature, strong acid and alkali environment, or under the action of specific catalysts, wonderful chemical reactions can also occur.
In summary, the physical properties of 4-methyl cinnamic acid lay the foundation for its application in the field of organic chemistry, allowing chemists to more precisely manipulate its participation in various reactions and create many novel and useful substances.

There are various methods for the synthesis of 4-methylcinnamic acid. One is to use styrene derivatives and malonic acid as raw materials and prepare them through Knoevenagel condensation reaction. This reaction needs to be catalyzed by weak bases to make the two condensate, eliminate a molecule of water, and generate 4-methylcinnamic acid. Weak bases such as pyridine can promote the orderly progress of the reaction. During the reaction, temperature control is quite important, and the ideal yield can be obtained usually in a suitable temperature range.
Second, using p-methylbenzaldehyde and acetic anhydride as starting materials, Perkin reaction is used to synthesize. In this process, acetic anhydride is in an alkaline environment, its α-hydrogen is taken away, and carbon negative ions are generated, which then undergo nucleophilic addition with p-methylbenzaldehyde, and then dehydration and other steps to obtain 4-methylcinnamic acid. The base used is often potassium acetate, etc. The reaction conditions also need to be precisely controlled. The temperature and reaction time are all related to the formation of the product.
Furthermore, it can be achieved by Wittig reaction. Using p-methylbenzaldehyde and phosphorus-ylide reagent, phosphorus-ylide reagent is prepared from halogenated hydrocarbons and triphenylphosphine first, and then treated with alkali. The two react to form a carbon-carbon double bond, thereby obtaining 4-methylcinnamic acid. The reaction conditions are relatively mild, but the preparation of the reagents may be slightly complicated.
There are also coupling reaction pathways catalyzed by transition metals. Select suitable transition metal catalysts, such as palladium catalysts, to couple alkenyl-containing halides or boric acid derivatives with p-methyl benzene derivatives to form carbon-carbon bonds to achieve the synthesis of 4-methyl cinnamic acid. This method has good selectivity, but the cost of the catalyst may be a consideration.
All synthesis methods have their own advantages and disadvantages. Experimenters should choose carefully according to actual needs, such as the availability of raw materials, cost, product purity requirements, etc., in order to achieve the desired synthesis effect.

4-Methyl cinnamic acid is in the market, and its price range is difficult to determine. Due to the complex market conditions, there are many variables.
Looking at past market conditions, prices often fluctuate due to changes in supply and demand, abundance of raw materials, difficulties in craftsmanship and policy guidance. If supply exceeds demand, the stock of goods is like a mountain, and the price may decline; if demand exceeds supply, there are many people in demand and few goods, and the price is easy to rise.
The production of raw materials is also the key. The raw materials are abundant, the sources are wide and the price is flat, and the cost of 4-methyl cinnamic acid decreases, and the price also follows; if the raw materials are scarce, the price is high and the cost increases, and the market price rises.
The refinement of the preparation process is also related to the price. If the process is excellent, the production is efficient and the cost is reduced, and the price has the power to reduce; if the process is sluggish, the production is low and the cost is high, and the price is difficult to decrease.
Policy regulations, or awards or restrictions, also have a huge impact. The policy of incentives, to promote the increase of production, the price may be stable or reduced; the policy of restriction and control, the production shrinkage is tight, and the price often rises.
In today's market, the price of 4-methyl cinnamic acid per kilogram may be between hundreds and thousands of yuan. However, this is only a rough estimate. The actual price should be confirmed by carefully observing the real-time market conditions and consulting the industry. It must not be based on this alone, but the price of the trade must be broken.