Ethyl 4 Methylcinnamate

Ethyl 4-methylcinnamate (ethyl 4-methylcinnamate) has a wide range of uses. In the field of fragrances, it exudes a unique fragrance, with a sweet floral and spicy aroma. It is like the first blooming of flowers in spring and has a pleasant aroma. Therefore, it is often used by perfumers. When blending perfumes and fragrances, it adds its charming charm, or gives the perfume an elegant tone, or adds its unique level to the fragrance, making it richer and longer lasting.
In the food industry, it can be used as a food fragrance because of its unique aroma. For example, in baked goods, it can create a warm and attractive aroma atmosphere, just like traditional cakes baked in the fire, emitting a rich and attractive fragrance, which makes the eater feel appetizing; in beverage preparation, it can also add a different flavor to the drink, which seems to inject agility into ordinary drinks, making their taste richer and more diverse.
Furthermore, in the field of pharmaceutical and chemical industry, this compound also has its uses. It can be used as an organic synthesis intermediate and participate in the synthesis process of many drugs and fine chemicals. For example, when synthesizing certain compounds with specific biological activities, their structural properties enable them to provide a key framework for the reaction, like building a building block that helps chemists build complex and functional molecular structures, which is of great significance for pharmaceutical research and development and fine chemical product innovation.

Ethyl 4-methylcinnamate (ethyl 4-methylcinnamate) is an organic compound with unique physical properties. Its color state is usually colorless to pale yellow liquid, and it looks clear and translucent, like the clear dew in the mountains in the morning, shimmering in the sun.
Its boiling point is about 285-286 ° C. At this temperature, molecules can break free from each other's attractive forces and change from liquid to gaseous state. Just like everything has a certain number, the boiling point is the limit of its jump from liquid to gaseous state.
The melting point is 16-18 ° C. When the temperature drops to this point, the molecular movement slows down, and the molecules are close to each other and arranged in an orderly manner. Substances solidify from liquid to solid state, just like time condenses, giving them a different form.
Relative density is about 1.02 - 1.03 g/cm ³, compared with water, slightly heavier than water, like a stable person, sinking quietly in water.
The refractive index is about 1.563 - 1.568. When light passes through this substance, the direction of propagation will change. This refractive property, like the twists and turns in life, makes the light path more abundant.
Ethyl 4 - methylcinnamate is insoluble in water, but soluble in organic solvents such as ethanol and ether. It is like a group of species. It can blend with organic solvents and accept each other. This solubility makes it possible to apply it in various chemical processes, opening a door to different reaction paths and playing an important role in fields such as organic synthesis.

Ethyl 4-methylcinnamate (ethyl 4-methylcinnamate), this is an organic compound. It has a fragrant taste and is mostly found in the field of fragrances, adding luster to the fragrance.
Looking at its chemical properties, it has the structure of unsaturated double bonds and ester groups. Unsaturated double bonds allow it to participate in the addition reaction. For example, when exposed to bromine water, the double bond can be added to bromine, causing the color of bromine water to fade. This is a typical reaction characterization. And under suitable catalytic conditions, it can be added to hydrogen and converted into a single bond. The existence of the
ester group makes it capable of hydrolysis. In an acidic environment, 4-methyl cinnamic acid and ethanol are hydrolyzed; in an alkaline environment, the hydrolysis is more thorough, resulting in 4-methyl cinnamate and ethanol. This hydrolysis reaction is a common characteristic of ester compounds.
Furthermore, because of the benzene ring in its structure, the stability of the benzene ring endows the compound with certain chemical stability, but it can also occur, such as the substitution reaction on the benzene ring. Depending on the reaction conditions and reagents, the corresponding substituents can be introduced at specific positions of the benzene ring. The various chemical properties of this compound make it important in many fields such as organic synthesis and fragrance preparation.

Ethyl 4-methylcinnamate is ethyl 4-methylcinnamate. The synthesis method is as follows:
First, 4-methylbenzaldehyde and malonic acid are used as raw materials, and the reaction is carried out in a pyridine solvent with a small amount of hexahydropyridine as a catalyst. This is a Knoevenagel condensation reaction. The pyridine is first placed in the reaction vessel, and then 4-methylbenzaldehyde and malonic acid are added in sequence, heated to a suitable temperature, and maintained for a certain period of time. Under the action of pyridine and hexahydropyridine, malonic acid enhances its carboxyl activity, condensates with the aldehyde group of 4-methylbenzaldehyde, decarboxylates to form 4-methylcinnamic acid, and then 4-methylcinnamic acid and ethanol are esterified under the catalysis of concentrated sulfuric acid to obtain ethyl 4-methylcinnamate. It should be noted that pyridine has a malodorous smell and has certain toxicity. When operating, it should be in a well-ventilated environment.
Second, 4-methylstyrene is used as raw materials with carbon monoxide and ethanol, and the reaction is carried out under the action of transition metal catalysts such as palladium. This is a hydroformylation-esterification tandem reaction. 4-Methylstyrene, ethanol and catalyst are placed in an autoclave, filled with an appropriate amount of carbon monoxide, controlled temperature and pressure, and reacted for a period of time. The double bond of 4-methylstyrene is hydroformylated with carbon monoxide and hydrogen to form an aldehyde intermediate, which is then esterified with ethanol and converted into ethyl 4-methylcinnamate. This method has high atomic utilization, but requires high pressure equipment and strict reaction conditions.
Third, ethyl acetoacetate and 4-methylbenzyl chloride are used as starting materials and react under alkaline conditions. First, ethyl acetoacetate is mixed with a base (such as sodium ethyl alcohol) to form ethyl acetoacetate into enol anion, and then 4-methyl benzyl chloride is added to undergo nucleophilic substitution reaction. The product is hydrolyzed and decarboxylated, and finally 4-methyl cinnamate is obtained. The raw materials used in this route are relatively common, but the reaction steps are slightly more, and the reaction conditions of each step need to be carefully controlled.

Ethyl 4 - methylcinnamate is an organic compound. When storing and transporting, all matters must be paid attention to.
First, it is related to storage. This compound should be placed in a cool, dry and well-ventilated place. Cover because of its certain chemical activity, high temperature and humid environment is easy to cause it to deteriorate. High temperature can promote chemical reactions, and humidity may cause adverse changes such as hydrolysis. And it must be kept away from fires and heat sources. Because organic compounds are flammable, there is a risk of combustion and explosion in case of open flames and hot topics. At the same time, they should be stored separately from oxidants, acids, and bases to avoid mixed storage.
Second, when transporting, there are also many key points. The transportation vehicle must ensure that the vehicle is in good condition and has corresponding fire protection and emergency equipment. The loading process should be lightly loaded and unloaded, and should not be operated brutally, so as to avoid damage to the packaging and leakage of Ethyl 4-methylcinnamate. If it is a long-distance transportation, the condition of the goods and the integrity of the packaging should also be checked regularly. During transportation, it is necessary to prevent exposure to the sun and rain. For example, when it is hot in summer, exposure to the sun will make the temperature in the car too high, which will affect the stability of the compound; rain may make the packaging damp, which will affect the internal materials. In the event of a leak, emergency measures should be taken immediately to evacuate the surrounding personnel. It is strictly forbidden for fire to approach, and the leakage should be properly handled according