What are the main uses of Methyl P-chlorocinnamate?
Methyl p-chlorocinnamate, this substance has a wide range of uses. In the field of organic synthesis, it is often a key raw material. Due to its unique structure, it can evolve many organic compounds with special properties through various reactions, such as participating in esterification, addition and other reactions, paving the way for the creation of complex organic molecules.
In the pharmaceutical and chemical industry, it also has outstanding performance. It can be used as a pharmaceutical intermediate to help develop new drugs. With its chemical activity, it can be cleverly combined with other compounds to shape substances with specific pharmacological activities, providing potential help for conquering diseases.
In the field of materials science, methyl p-chlorocinnamate has also made a name for itself. Polymer materials with specific optical and electrical properties can be prepared by polymerization and other means, such as for optical lenses, electronic components, etc., which contribute to the manufacture of modern scientific and technological products.
Furthermore, in the fragrance industry, due to its unique chemical structure, it may endow fragrances with a different flavor, providing the possibility to formulate novel and unique fragrances, and enhancing the richness and attractiveness of fragrance products. In short, methyl p-chlorocinnamate plays an important role in many fields, and is of great significance in industrial production and scientific research.
What are the physical properties of Methyl P-chlorocinnamate?
Methyl-p-chloro-cinnamic acid methyl ester is a kind of organic compound. It has unique physical properties, which are described in detail by you.
Looking at its properties, under normal temperature and pressure, it is mostly white to light yellow crystalline powder, which is easy to identify. Its melting point is in a specific range, about 45-48 degrees Celsius. When heated to this temperature range, this substance gradually melts from a solid state to a liquid state. This melting point characteristic is of great significance in the identification and purification of compounds.
As for the boiling point, under the corresponding conditions, it is about 300 degrees Celsius. The value of the boiling point is related to the volatility of the compound. This boiling point indicates that methyl-p-chlorocinnamate has low volatility and is relatively stable in ordinary environments.
Solubility is also an important physical property. This substance is insoluble in water, but it can be soluble in organic solvents such as ethanol, ether, and chloroform. This difference in solubility is related to the molecular structure of the compound. Due to the characteristics of the groups contained in the molecule, it interacts weakly with water molecules, but can be well miscible with organic solvent molecules. This property is widely used in organic synthesis for extraction and reaction medium selection.
In addition, methyl-p-chlorocinnamate methyl ester has a certain aroma. Although it is not strong and pungent, it has a unique fragrance. This property also makes it potentially useful in the field of fragrance blending.
From the above physical properties, methyl-p-chlorocinnamate methyl ester plays an important role in the synthesis, separation, application and many other aspects in the field of organic chemistry due to its interrelated properties. It has made great contributions to the development of organic synthesis and related industries.
What are the chemical properties of Methyl P-chlorocinnamate?
Methyl p-chlorocinnamate is a kind of organic compound. Looking at its chemical properties, this substance contains carbon-carbon double bonds and can develop an addition reaction. In case of suitable reagents, the double bonds can be added to hydrogen halides, halogens, etc. If it meets bromine water, the bromine element will be added to the double bond, causing the bromine water to fade. This is a common means to test the double bond.
Because of its ester group, hydrolysis can occur in an acid or base-catalyzed environment. In acidic media, hydrolysis produces p-chlorocinnamic acid and methanol; in alkaline conditions, hydrolysis generates p-chlorocinnamic acid and methanol, and the presence of alkali promotes the hydrolysis reaction to be more complete.
The benzene ring structure of methyl p-chloro-cinnamate allows it to undergo typical reactions of aromatic hydrocarbons, such as electrophilic substitution reactions. The electron cloud density on the benzene ring is high, making it vulnerable to electrophilic attack. Common electrophilic substitution reactions include halogenation, nitration, sulfonation, etc. Due to the localization effect of chlorine atoms and ester groups, the substitution reaction mostly occurs at specific positions in the benzene ring.
Furthermore, under specific conditions, the substance may participate in the polymerization reaction. The activity of carbon-carbon double bonds gives it the opportunity to be used as a monomer, through addition polymerization, to form a polymer, which provides the possibility for applications in the field of materials science.
In addition, methyl p-chlorocinnamate has a certain stability, but under extreme conditions such as high temperature and strong oxidants, the structure may be damaged. Its physical properties also affect its chemical behavior, such as solubility, melting point, boiling point, etc., which will affect the progress of the reaction and the separation of the product. In organic synthesis and industrial production, it is of great significance to fully consider and utilize these chemical properties to prepare the target product and optimize the reaction path.
What is the synthesis method of Methyl P-chlorocinnamate?
The method of making methyl p-chloro-cinnamic acid methyl ester is an ancient organic synthesis, and it follows a classic path. At the beginning, it is often based on p-chlorobenzaldehyde and malonic acid, and under the catalysis of weak bases such as pyridine or hexahydropyridine, Knoevenagel condensation is carried out. In the case of weak bases, the carboxyl activity of malonic acid increases, and the aldehyde group is added to it nucleophilic, followed by dehydration to produce p-chloro-cinnamic acid. This step also controls the temperature of the reaction and is suitable for a mild environment. If it is covered with high temperature, side reactions will occur, resulting in loss of yield.
Second, p-chloro-cinnamic acid is mixed with methanol, and sulfuric acid or p-toluenesulfonic acid is added as a catalyst to carry out Although sulfuric acid is strongly catalyzed, there is a risk of carbonization of substrates, while p-toluenesulfonic acid is slightly slower and more stable. In this reaction, the azeotropic method can be used to remove water, which can promote the right shift of equilibrium and increase the yield of esters.
There is also a method of phase transfer catalysis. In the heterogeneous system, quaternary ammonium salt or crown ether are used as phase transfer catalysts to increase the reaction speed, and the conditions are mild and the yield is also good. Among them, the amount of catalyst, the time of reaction, and the temperature need to be fine-tuned to obtain good results. During operation, the ratio of materials, the speed of stirring, and the efficiency of removing water are all the keys to success or failure. At the time of refining, or by distillation and recrystallization to extract the purity of the product, methyl p-chlorocinnamate is finally obtained.
What is the price range of Methyl P-chlorocinnamate in the market?
The market price of methyl parachlorocinnamate varies due to many factors. This product has a wide range of uses and is used in medicine, fragrance and other industries. Its price often depends on quality, purity, and market supply and demand.
If the quality is high and the purity is good, the price may be high; and if the purity is slightly lower, the price should be slightly lower. On the supply and demand side of the market, if there are many people who want it, the supply is small, and the price may decrease.
Today in the market, the price range is about hundreds to thousands of yuan per kilogram. If it is of ordinary purity, it can cost several hundred yuan per kilogram; while the price of high-purity high-quality products can reach several thousand yuan per kilogram. However, this is only a rough estimate. The market situation changes, and the actual price must be obtained by consulting the relevant suppliers or market surveys. To determine the accurate price, when observing the real-time dynamics of the market and studying all the influencing factors, the true price can be obtained.