Methyl P-Chlorocinnamate

Methyl P - Chlorocinnamate (methyl p-chlorocinnamate) is widely used. In the field of fragrance, it can add a unique charm to the fragrance. Because of its special aroma, the cap can be used to prepare various fragrances, such as daily flavors, to make the product emit a charming smell and increase pleasure.
In the field of pharmaceutical and chemical industry, it also occupies an important place. Or it can be a key intermediate for the synthesis of many drugs. Through specific chemical reactions, it helps pharmaceutical developers to produce drugs with therapeutic effects, or drugs involved in antibacterial, anti-inflammatory and other effects, which is of great significance to human health.
In the field of organic synthesis, it is a common raw material. Chemists can use it as a starting material to build complex organic molecular structures through various organic reactions, expand the boundaries of organic synthetic chemistry, and lay the foundation for the research and development of new materials. It is a key link in the chain of the chemical industry, maintaining the production and innovation of many products.

The physical properties of methyl p-chlorocinnamate are as follows.
Looking at its morphology, at room temperature, it is mostly white to off-white crystalline powder. This shape is easy to identify, and in many operations, the powder is easy to handle and weigh. Its melting point is quite critical, about [specific melting point value], and the stability of the melting point provides an important basis for the identification of this substance and the setting of relevant reaction conditions.
Discusses solubility, the substance exhibits a specific tendency in organic solvents. In common organic solvents such as ethanol, acetone, etc., it has a certain solubility. This property makes it possible to select an appropriate solvent system according to its solubility in the process of synthesis, purification and subsequent preparations to achieve effective separation and reaction. In water, its solubility is poor, which also determines that its application in aqueous systems is limited, but it is of unique significance in the chemical reaction and preparation development of organic phases.
Furthermore, its density is also one of the important physical properties, about [specific density value]. The parameters of density have a great impact on the material ratio, mixing and storage, etc., which are related to the uniformity of the reaction system and the stability of storage.
In addition, its odor is weak, and its stability is relatively good. Under conventional storage conditions, it can maintain the stability of its chemical structure and properties, which provides great convenience for long-term storage and application in different environments.
In summary, these physical properties of methyl p-chlorocinnamate play a crucial role in its synthesis, application and storage, laying the foundation for its rational use in many fields.

The chemical synthesis of methyl p-chlorocinnamate is an important research direction in the field of organic synthesis. In the past, the method used p-chlorobenzaldehyde and malonic acid as the starting materials. Under the action of basic catalysts such as pyridine, it underwent Knoevenagel condensation reaction to form p-chlorocinnamate, and then esterified with methanol under the catalysis of concentrated sulfuric acid to obtain the target product.
Although this traditional route can obtain the product, it also has many drawbacks. For example, concentrated sulfuric acid as a catalyst has strong corrosiveness, strict requirements for reaction equipment, and complicated post-reaction treatment, which is prone to generate a large amount of wastewater, which does not match the concept of green chemistry. Furthermore, the Knoevenagel condensation reaction conditions are relatively harsh, and the temperature and the proportion of reactants need to be strictly controlled, otherwise the yield will not be good.
There is an improved method after using a phase transfer catalyst, which can make the reaction proceed under milder conditions and improve the reaction rate and yield. There are also ionic liquids as the reaction medium. Ionic liquids have the advantages of low volatility and high stability, which can improve the reaction selectivity, and can be reused to reduce environmental pollution. In addition, enzyme-catalyzed synthesis methods have also emerged. Enzyme catalysis has the characteristics of high efficiency and specificity, and the reaction conditions are mild, which can effectively avoid the shortcomings of traditional methods. However, the high cost and poor stability of enzymes limit their large-scale application.
Other new technologies such as microwave radiation and ultrasonic assistance are used for its synthesis. Such technologies can accelerate the reaction process, improve the reaction efficiency, and reduce the amount of catalyst, opening up new paths for the synthesis of methyl p-chlorocinnamate. However, microwave and ultrasonic equipment are expensive and the technical requirements are relatively complicated.

Methyl p-chlorocinnamate should pay attention to many matters during storage and transportation. This compound has specific chemical properties. First, it is necessary to avoid open flames and hot topics. Because of its flammability, in case of open flames and hot topics, it is easy to cause the risk of combustion, causing serious accidents and endangering personal and property safety.
Second, it should be placed in a cool and ventilated warehouse. A cool environment can prevent its chemical properties from changing or accelerating deterioration due to excessive temperature; good ventilation can disperse harmful gases that may evaporate, reduce the concentration of accumulation, and avoid the formation of dangerous environments.
Furthermore, it should be stored separately from oxidants, acids, etc. This is due to the chemical activity of methyl p-chlorocinnamate, contact with oxidants, or trigger violent oxidation reactions; coexistence with acids may also cause chemical reactions, cause product deterioration, and even form dangerous products.
When transporting, also ensure that the container does not leak, collapse, fall, or damage. The packaging needs to be strong and can withstand bumps and collisions during transportation. And the transportation process should follow the specified route, do not stop in densely populated areas and residential areas, to prevent accidental leakage from causing harm to many people. In short, regardless of storage or transportation, it is necessary to strictly abide by relevant norms and requirements to ensure safety.

Methyl p-chlorocinnamate, the market price, is not constant. The range of its price varies due to various reasons.
First, the price of raw materials is also. The production of this product requires specific raw materials, and the abundance of raw materials and the supply and demand of the market can determine its price. If the raw material is rare and the number of people are seeking it, the price will be high; otherwise, the price may drop.
Second, the method of production is also the same as the original. A refined method can reduce costs and increase efficiency. If the method is clumsy, the original will increase, and the price will also be high. And the cost of equipment and labor is also involved in the price.
Third, the supply and demand of the market. If the demand is wide, the supply is not enough, and the price must go up; if the supply exceeds the demand, the price may fall.
Fourth, the difference between regions. In different places, the transportation fee and tax vary, resulting in different prices. In distant places, the transportation distance is long, the cost is high, and the price is high.
Roughly speaking, the price of methyl p-chlorocinnamate varies from tens to hundreds of yuan per kilogram. However, this is only an approximate number, and the actual price must refer to the current market situation, the quantity purchased, and the quality of the product. To know the exact price, you can consult the supplier, trader, or observe the reports of the chemical market to obtain the information.