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What are the main uses of Cinnamyl Chloride?
Cinnamyl chloride (Cinnamyl Chloride) has a wide range of uses and is used in various fields.
First, in the field of medicine, cinnamyl chloride is often an important synthetic raw material. Based on it, a variety of drugs can be prepared. Due to its unique structure, it has certain biological activities. Through specific chemical reactions, it can be combined with other compounds to build complex drug molecular structures, resulting in drugs with therapeutic effects, or antibacterial, anti-inflammatory and other effects, which add to the research and development of medicine.
Second, in the field of organic synthesis, cinnamyl chloride is also a key reagent. Organic chemists rely on it for various reactions, such as acylation reactions. It can react with alcohols, amines and other compounds to generate corresponding esters and amides. Such products are widely used in fine chemical products, such as the preparation of fragrances, cosmetic additives, etc.
Third, cinnamyl chloride is also common in the fragrance industry. Because it can participate in the synthesis of compounds with unique aroma, it can add the complexity and uniqueness of the fragrance, make the fragrance more rich and rich, and then improve the quality and market competitiveness of fragrance products.
Fourth, in the field of materials science, some polymers or composites prepared by the reaction of cinnamyl chloride have special physical and chemical properties. It can enhance the stability and mechanical properties of materials and play an important role in the research and development and production of high-tech materials.
Overall, cinnamyl chloride is an indispensable chemical in many fields such as medicine, organic synthesis, fragrance and material science, promoting technological progress and product innovation in various fields.
What are the Physical Properties of Cinnamyl Chloride?
Cinnamyl chloride (Cinnamyl Chloride) is an important compound in organic chemistry. Its physical properties are unique and have the following characteristics:
Under normal temperature, cinnamyl chloride appears as a colorless to light yellow liquid. This color is distinct and easy to identify. Its unique smell emits a pungent smell, which makes people alert to its chemical activity.
When it comes to the melting point, the melting point is about -7.5 ° C. The lower melting point causes it to exist as a liquid at room temperature. The boiling point is about 256-258 ° C. A relatively high boiling point indicates that the intermolecular force is strong, and a higher temperature is required to vaporize it.
The density of cinnamyl chloride is also an important physical property. About 1.129 (g/mL, 20 ° C), this density is slightly larger than that of water, so when mixed with water, it will sink to the bottom.
In terms of solubility, cinnamyl chloride is insoluble in water, but soluble in organic solvents such as ethanol, ether, chloroform, etc. This solubility property is related to its molecular structure. The non-polar structures such as phenyl ring and carbon-carbon double bond contained in its molecule make it have good compatibility with non-polar organic solvents.
In addition, the volatility of cinnamyl chloride cannot be ignored. Although it is not very volatile, it will still evaporate slowly and spread in the air under certain temperature and environmental conditions. This property requires attention during storage and use to prevent its volatilization from causing loss or causing safety issues.
In summary, the physical properties of cinnamyl chloride are diverse, and their applications in chemical synthesis, medicine, fragrances and other fields are closely related to their physical properties. Only by familiar with and mastering their physical properties can this compound be used more properly.
What are the precautions for Cinnamyl Chloride during storage?
For cinnamyl chloride, there are various things to pay attention to during storage. First, this is a corrosive chemical, which is active and easily reacts with water and alcohols. Therefore, when stored in a dry, cool and well-ventilated place, it should never be close to water, humid air and alcohols to prevent deterioration. In case of water, it will quickly hydrolyze, causing cinnamic acid and hydrogen chloride to damage its quality, and hydrogen chloride is irritating, endangering the environment and people.
Second, cinnamyl chloride is sensitive to light, and under light, it may decompose or cause side reactions. When storing, it is appropriate to use an opaque container and place it in a dark place to maintain its chemical stability and reduce the possibility of decomposition.
Third, its volatility is strong, and the storage device must be tightly sealed. If the seal is not good, cinnamyl chloride evaporates in the air, which not only causes material loss, but also causes damage to the health of the operator because the product is irritating, and it evaporates in the air, or reacts with other substances, causing safety hazards.
Fourth, it should be stored separately from oxidants and strong bases. Cover cinnamyl chloride is chemically active, coexists with oxidants, or reacts violently, with the risk of explosion; when it encounters strong bases, it is also easy to react, affecting quality and safety.
When storing cinnamyl chloride, care must be taken to prevent water, light, sealing and compatibility with other chemicals to ensure its quality and storage safety.
What are the Synthetic Methods of Cinnamyl Chloride
There are various ways to synthesize cinnamyl chloride. First, cinnamyl acid and sulfoxide chloride are used as raw materials. The two are heated in a suitable container with an appropriate amount of catalyst, such as N, N-dimethylformamide (DMF). The chlorine atom of sulfoxide chloride replaces the hydroxyl group of cinnamyl acid, resulting in cinnamyl chloride, and by-product sulfur dioxide and hydrogen chloride gas. This reaction is relatively common, because its raw materials are easy to find and the reaction conditions are not harsh. However, attention should be paid to the treatment of exhaust gas to prevent environmental pollution.
Second, cinnamyl alcohol is reacted with chlorination reagent. If phosphorus trichloride is used as a chlorination agent, cinnamyl alcohol is mixed with phosphorus trichloride. At a specific temperature and reaction time, the hydroxyl group of cinnamyl alcohol is replaced by chlorine atoms to obtain cinnamyl chloride. In this process, phosphorus trichloride is converted into phosphoric acid. This method is also used, but phosphorus trichloride is corrosive, so caution must be taken during operation.
Third, use the phase transfer catalysis method. Select a suitable phase transfer catalyst, such as quaternary ammonium salts. In the reaction system of cinnamic acid and chlorinated reagents (such as dichlorosulfoxide), the phase transfer catalyst can promote the reaction to proceed efficiently between different phases, accelerate the reaction rate, and increase the yield of cinnamyl chloride. And this method can be operated under relatively mild conditions, and the equipment requirements are not very high, so it has also attracted attention in synthesis practice.
All these synthesis methods have their own advantages and disadvantages, and they need to be carefully selected according to the actual situation, such as raw material cost, equipment conditions, product purity requirements, etc., to achieve the best synthesis effect.
What is the market price range for Cinnamyl Chloride?
Cinnamyl chloride is a commonly used reagent in organic synthesis. Its market price range often varies due to many factors, making it difficult to generalize.
In the past, the price of cinnamyl chloride was mostly determined by the cost of raw materials, the preparation process, and the state of market supply and demand. If the raw materials are abundant and the preparation method is simple, the price may be low; conversely, if the raw materials are scarce and the preparation is complicated, the price will be high.
Under normal market conditions, the price of cinnamyl chloride with average purity may range from hundreds to thousands of yuan per kilogram. If its purity is extremely high, reaching the level of scientific research, and used for high-end experimental research, its price will be higher, or to tens of thousands of yuan per kilogram.
In addition, changes in market supply and demand also have a great impact on price. If there is a large increase in demand for cinnamyl chloride at a certain time, but the supply is limited, the price will rise; if the demand is weak and the supply is excessive, the price may be low.
Furthermore, different suppliers sell cinnamyl chloride at different prices due to differences in cost control and brand effect. Therefore, in order to know the exact market price range of cinnamyl chloride, it is necessary to carefully observe the current market situation and compare the quotations of various suppliers in multiple parties to obtain a more accurate figure.